I en studie publicerad i Human Reproduction 1998 jämfördes resultaten vid 95 Surrogatgraviditeter med vanligt IVF behandling. De parametrar man bl.a. tittade på var födelsevikten, andelen tvillingfödslar samt risken att drabbas av graviditetshypertoni och blödning under sista 3:e delen av graviditeten. Resultatet visade att de kvinnor som varit surrogatmammor hade 4-5 ggr lägre risk att drabbas av komplikationer i graviditeten i form av blödning eller för högt blodtryck jämfört med kvinnor som får vanlig IVF behandling. Sammanfattningsvis visar studien på goda resultat med låga medicinska risker för surrogatmödraskap jämfört med vanlig IVF behandling, både för de kvinnor som är surrogatmamma och de barn som föds.
Nedan kan du läsa den engelska sammanfattningen och gå gärna vidare och läs artikeln i sin helhet i den vetenskapliga tidskriften Human Reproduction.
Human Reproduction vol.14 no.3 pp.671–676, 1998
Perinatal outcome after in-vitro fertilization-surrogacy
Judy Parkinson, Cuong Tran, Tih Tan, Jeffrey Nelson, Joel Batzofin and Paulo Serafini
The perinatal outcome of pregnancies (both single and multiple) established after in-vitro fertilization (IVF)-surrogacy was evaluated and compared to the outcome of pregnancies that resulted from standard IVF. Analysis of medical records and a telephone interview with physicians, IVF-surrogates, and commissioning mothers were conducted to assess prenatal follow up and delivery care in several hospitals. 95 IVF-surrogates delivered 128 liveborn (65 singletons, 27 sets of twins and two sets of triplets). The commissioning mothers and the IVF-surrogates average ages were 37.7 K 5.0 and 30.4 K 4.7 years old respectively. IVF-surrogates carrying twin and triplet gestations delivered substantially earlier than those who gestated singleton pregnancies (36.2 K 0.4 versus 35.5 versts 38.7 K 0.3 weeks gestation respectively; P < 0.001). Twin newborns were significantly lighter than singleton infants born through IVF-surrogacy (2.7 K 0.06 versus 3.5 K 0.07 kg; P < 0.001). The incidence of low birth weight infants rose from 3.3% in the single births to 29.6% (P < 0.01) in the twins and to 33.3% in the triplets born through IVFsurrogacy. The incidence of prematurity was significantly greater in both twins delivered by IVF-surrogates (20.4%) and infertile IVF patients (58%). The occurrence of pregnancy-induced hypertension and bleeding in the third trimester was four to five times lower in the IVF-surrogates, independently of whether they were carrying multiples. The incidence of Caesarean section was 21.3% for singleton gestations, while two times higher in the IVF-surrogates carrying multiples (56.3%). Postpartum complications occurred in 6.3% of patients and the incidence of malformation was similar to those reported for the general population.
The results provide general reassurance regarding perinatal outcome to couples who wish to pursue IVFsurrogacy.